Publications & Media
Impactful Publications
Over 178 Acknowledged or Co-Authored with GTAC@MGI
Our featured media for the month to recognize the research accomplishments of our collaborators and customers.
PPAR Research
“Our research program has benefited tremendously from support we have had from the GTAC. This has included both a wide range of technical services, including quality assessments, library preparation, and sequencing of samples from RNA- and ChIP-Seq experiments, as well as collaborative data analysis support, which, together, has directly contributed in substantive ways to the publications listed below, presentations at national meetings, and ongoing collaborative projects. We are very grateful for and intend to continue utilizing these exceptional resources which have accelerated the advancement of our research program.”
Dr. David A. Rudnick
Results produced by RNAseq with Illumina sequencers.
Science
“GTAC@MGI provides an outstanding range of genomic, proteomic and bioinformatics capabilities, coupled with first class support, responsiveness and innovation. We have benefited tremendously from their expertise in large-scale DNA/RNA sequencing (e.g. Illumina NovaSeq), aptamer-based proteomics (SomaLogic SomaScan) and multiplexed qPCR assay design and execution (Fluidigm Biomark HD), to name just a few. Their innovative knowledge generation algorithm ‘CompBio’ takes interpretation of large multi-omic datasets to another level. CompBio performs an automated extraction of knowledge from all PubMed abstracts containing terms relevant to your dataset, and uses conditional probability analysis to compute the statistical enrichment of contextually associated biological concepts/themes. This has generated numerous novel insights into the biological effects of our ‘microbiota-directed’ foods on host physiology; moreover, having also spent many years in Pharma, I can vouch firsthand for the uniqueness and power of this tool for data interpretation and hypothesis generation.”
Dr. Mike Barratt
Technologies included SomaScan and Fluidigm qPCR enteropathogen assay.
Cell Metabolism
“Within the past 5 years our focus changed from exclusively bone cell biology to the relationship of adipose tissue and the skeleton. In the course of these studies we faced opportunities to identify a unique macrophage genotype which completely prevents diet induced obesity and signaling pathways activated by ablation of adiponectin expressing cells which induce massive bone formation. We turned to members of GTAC to assist us. They enthusiastically agreed and their efforts were central to publications in high impact journals which they co-authored as well as a recently funded Department of Defense grant. We at Washington University are fortunate to have this resource and especially very collaborative GTAC members.”
Dr. Steven Teitelbaum
Illumina Next generation sequencing for RNA-seq.
CLINICAL CHEMISTRY
Detection with RT-LAMP for SARS-CoV-2 by GTAC@MGI researchers.
Nature
Work supported with high-performance genomic analysis.
News
PercayAI and Saint Louis University Partner to Accelerate AI Adoption across Biomedical Sciences Research
Washington University pumps millions into Cortex building, as another rises nearby
Washington U. School of Med. deploys COVID saliva testing
PercayAI’s software helps researchers discover and develop more effective medicines faster than traditional methods.
Washington University is investing millions of dollars in a decades-old building near Cortex, helping boost occupancy there as another 11-story research development rises nearby.
Washington University School of Medicine, using a $5 million grant from the National Institutes of Health, has begun administering the COVID-19 saliva test it developed in the Special School District of St. Louis County in search of asymptomatic carriers among teachers initially.