Not Just Data… Answers

Providing cutting-edge and cost-effective sequencing and analysis technologies

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New Submission System

The GTAC@MGI has launched a new online submission system for Service Requests for Illumina sequencing, library prep, and sample QC services. Please Register for an account using your institutional email address as your Username and complete new requests here.

Please NOTE that the platform for our legacy GTAC online submission system will no longer be supported by WashU IT; therefore, user access to this system will not be possible after 12/15/22. If you want to keep a copy of any service requests made to the GTAC with this system, please login prior to 12/15/22 to download or save a copy of any requests here.  If you encounter login issues, please reach out to Toni Sinnwell [sinnwellt@wustl.edu] and Jen Doias [jdoias@wustl.edu] to request assistance.

Our Breaking Technology

Single- cell exploration continues with Smart-seq2.  If you would like to learn more about this  breaking technology click the link below.

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Our Feature Technology

Single cell Multiome ATAC+ Gene Expression allows for understanding the transcriptome and the epigenome at the same time. If you would like to learn more about this breaking technology click the link below.

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Learn About Our Laboratory Services

As these are just a few of our highlighted products and services, we do offer many more beyond what is listed here, including custom solutions. 

Microarray

Express thousands of genes at the same time

Specimen Processing

Isolate DNA or RNA from a variety of specimens

PCR

Quantify Genes through Targeted Sequencing, SNP Genotyping, & Gene expression

Illumina Sequencing

Sequence nucleotides in small targeted genomic regions or entire genomes

Gene Expression Panels

Quantify gene expression with specialized probes

Whole Genome Mapping

Resolve DNA structural variation or recreate a whole-genome map assembly

For more details on these and other Laboratory Services that we offer, click the “Laboratory Services” button.

Laboratory Services

Other Service Options

Facilitates collaborators and customers with functional genomic studies through the use of patient-derived iPSCs and the generation of modified cells and organisms using genome editing technologies.

Provides physicians with clinically validated next-generation sequencing for cancer, somatic overgrowth, and a variety of constitutional diseases. 

The Elizabeth H. and James S. McDonnell III Genome Institute provide comprehensive genomic services to Washington University and the scientific community.

Need Help With A Project?

GTAC@MGI’s dedicated project development and management team routinely assists investigators with designing the most informative sequencing and analysis strategies at minimal cost. Our specialized customer service provides a connection to the facility and the research.

Email

gtac-mgi-list@email.wustl.edu

Meet Our Team

GTAC@MGI’s staff are a highly qualified team of experts representing multiple departments across Washington University in St. louis, including Medicine, Genetics, Pathology, Pediatrics and Neurology.

Richard Head
Director

Shelly O’Laughlin​
Clinical Operations

Michael Heinz
Research Operations

For more details on these and other members of our distinguished team, click the “Our Team” button.

Our Team

Our Partners

Collaborations provide additional ways to connect the researcher to their science.

Integrated DNA Technologies

Bionano Genomics

PacBio

For more details on these and other partners, click the “Our Partners” button.

Our Partners

Not Sure What You Need?

GTAC@MGI’s Technology Guidance Services and Resources may be of some help.  Click the Learn More button to navigate to our Technology Guidance page to learn more about the  equipment and technologies that we have currently available.
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What Our Collaborators Say

Our research program has benefited tremendously from support we have had from the GTAC. This has included both a wide range of technical services, including quality assessments, library preparation, and sequencing of samples from RNA- and ChIP-Seq experiments, as well as collaborative data analysis support, which, together, has directly contributed in substantive ways to the publications listed below, presentations at national meetings, and ongoing collaborative projects. We are very grateful for and intend to continue utilizing these exceptional resources which have accelerated the advancement of our research program.

Publications That Demonstrate GTAC@MGI’s Service Options
Identification of an epigenetic signature of early mouse liver regeneration that is disrupted by Zn-HDAC inhibition
Postponing the Hypoglycemic Response to Partial Hepatectomy Delays Mouse Liver Regeneration
Diet Modifies Pioglitazone’s Influence on Hepatic PPAR γ-Regulated Mitochondrial Gene Expression

David Rudnick

Associate Professor of Pediatrics

My experience in dealing with GTAC was extremely gratifying. I was able to discuss the study design ahead of time so that I had a sufficient sample size to address my scientific questions. GTAC also helped me work through the best way to analyze and present the large data sets in a simplified format that facilitated my ability to effectively communicate our findings to the scientific community.

Publications That Resulted from GTAC@MGI services
Myocardial B cells are a subset of circulating lymphocytes with delayed transit through the heart
Proteomic Signatures of Heart Failure in Relation to Left Ventricular Ejection Fraction
Developmental changes in myocardial B cells mirror changes in B cells associated with different organs

Douglas Mann

Tobias & Hortense Lewin Professor of Medicine

Breaking Technology

Smart-Seq2

As single-cell exploration continues to evolve GTAC@MGI highlights a possible future option.  SMART-seq2 allows for accurate transcriptome analysis from a single cell.   This process grants the ability for full-length RNA-seq to be reviewed from a single cell. To further understand the process check out the paper, “Full-length RNA-seq from single cells using Smart-seq2”. 

Single Cell Multiome ATAC + Gene Expression

Interested in researching the transcriptome and the epigenome in a single cell?  Approach it multidimensionally with the single cell Multiome ATAC + Gene Expression process.  Check out this video to understand it better.

Leading the way in high-speed, comprehensive genomics

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Address

4444 Forest Park Ave, Campus Box 8501
St. Louis, MO 63108

Email

gtac-mgi-list@email.wustl.edu