Not Just Data… Answers
Providing cutting-edge and cost-effective sequencing and analysis technologies
Our Breaking Technology
Single- cell exploration continues with Smart-seq2. If you would like to learn more about this breaking technology click the link below.
Need additional services?
Genome Engineering and iPSC Center They will facilitate your functional genomic studies through the use of patient-derived iPSCs and the generation of modified cells and organisms using genome editing technologies.
Genomics and Pathology Services Provides physicians with clinically validated next-generation sequencing for cancer, somatic overgrowth, and a variety of constitutional diseases.
The Elizabeth H. and James S. McDonnell III Genome Institute Learn more about the comprehensive genomic services including outreach to the St. Louis community
Our Feature Technology
Single cell Multiome ATC+ Gene Expression allows for understanding the transcriptome and the epigenome at the same time. If you would like to learn more about this breaking breaking technology click the link below.
Learn About Our Laboratory Services
As these are just a few of our highlighted products and services, we do offer many more beyond what is listed here, including custom solutions.
Microarray
Express thousands of genes at the same time
Specimen Processing
Isolate DNA or RNA from a variety of specimens
PCR
Quantify Genes through Targeted Sequencing, SNP Genotyping, & Gene expression
Illumina Sequencing
Sequence nucleotides in small targeted genomic regions or entire genomes
Gene Expression Panels
Quantify gene expression with specialized probes
Whole Genome Mapping
Resolve DNA structural variation or recreate a whole-genome map assembly
For more details on these and other Laboratory Services that we offer, click the “Laboratory Services” button.
Other Service Options
Need Help With A Project?
Meet Our Team
GTAC@MGI’s staff are a highly qualified team of experts representing multiple departments across Washington University in St. louis, including Medicine, Genetics, Pathology, Pediatrics and Neurology.
For more details on these and other members of our distinguished team, click the “Our Team” button.
Our Partners
Collaborations provide additional ways to connect the researcher to their science.
For more details on these and other partners, click the “Our Partners” button.
Not Sure What You Need?
GTAC@MGI’s Technology Guidance Services and Resources may be of some help. Click the Learn More button to navigate to our Technology Guidance page to learn more about the equipment and technologies that we have currently available.
What Our Collaborators Say
Our research program has benefited tremendously from support we have had from the GTAC. This has included both a wide range of technical services, including quality assessments, library preparation, and sequencing of samples from RNA- and ChIP-Seq experiments, as well as collaborative data analysis support, which, together, has directly contributed in substantive ways to the publications listed below, presentations at national meetings, and ongoing collaborative projects. We are very grateful for and intend to continue utilizing these exceptional resources which have accelerated the advancement of our research program.
Publications That Demonstrate GTAC@MGI’s Service Options
Identification of an epigenetic signature of early mouse liver regeneration that is disrupted by Zn-HDAC inhibition
Postponing the Hypoglycemic Response to Partial Hepatectomy Delays Mouse Liver Regeneration
Diet Modifies Pioglitazone’s Influence on Hepatic PPAR γ-Regulated Mitochondrial Gene Expression
David Rudnick
My experience in dealing with GTAC was extremely gratifying. I was able to discuss the study design ahead of time so that I had a sufficient sample size to address my scientific questions. GTAC also helped me work through the best way to analyze and present the large data sets in a simplified format that facilitated my ability to effectively communicate our findings to the scientific community.
Publications That Resulted from GTAC@MGI services
Myocardial B cells are a subset of circulating lymphocytes with delayed transit through the heart
Proteomic Signatures of Heart Failure in Relation to Left Ventricular Ejection Fraction
Developmental changes in myocardial B cells mirror changes in B cells associated with different organs
Douglas Mann
Breaking Technology
Smart-Seq2
As single-cell exploration continues to evolve GTAC@MGI highlights a possible future option. SMART-seq2 allows for accurate transcriptome analysis from a single cell. This process grants the ability for full-length RNA-seq to be reviewed from a single cell. To further understand the process check out the paper, “Full-length RNA-seq from single cells using Smart-seq2”.
Featured Technology
Single Cell Multiome ATAC + Gene Expression
Interested in researching the transcriptome and the epigenome in a single cell? Approach it multidimensionally with the single cell Multiome ATAC + Gene Expression process. Check out this video to understand it better.