Not Just Data… Answers

The Genome Access Technology Center at the McDonnell Genome Institute leads the world and the St. Louis community in the fast-paced, fluid field of genomics. ​ With always versatile offerings of next generation sequencing, microarray, PCR, Bioinformatic services, and other comprehensive options so that can complete our collaborators’ research needs.  In addition to generating high quality genomic, transcriptomic, and even proteomic data, we also perform data analysis and provide technological support to users to ensure maximum data value and understanding of the results.

Not Just Data… Answers

The Genome Access Technology Center at the McDonnell Genome Institute leads the world and the St. Louis community in the fast-paced, fluid field of genomics. ​ With always versatile offerings of next generation sequencing, microarray, PCR, Bioinformatic services, and other comprehensive options so that can complete our collaborators’ research needs.  In addition to generating high quality genomic, transcriptomic, and even proteomic data, we also perform data analysis and provide technological support to users to ensure maximum data value and understanding of the results.

400+ Publications Annually
60K-100K Samples Annually
30+ Years of Genomic Research
400+ Collaborators Annually
3.5+ PBs SeqData Annually

Core Technologies

News

Announcement

GTAC@MGI has released a new services/ordering tool for project submissions:
washu.microsoftcrmportals.com/

New Technologies coming soon in 2023!

  • Illumina NovaSeq X Plus sequencers ordered!!
  • PacBio Revio sequencer ordered!!
  • New assays coming online for Oxford Nanopore Promethion sequencing (WGS, Isoseq)
  • 10X Genomics Xenium for targeted, highresolution spatial transcriptomics
  • 10X Genomics fixed singlecell RNAseq assays

Recently added technologies/services

  • Somalogic SomaScan 7K proteomic assay for serum, plasma, cerebrospinal fluid, urine, or other equally small amounts of
    biological matrices, such as lysates.
  • 10X Genomics Visium spatial transcriptomics assay for FFPE specimens

Highlighted Publications

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Need Help With A Project?

GTAC@MGI’s dedicated project development and management team routinely assists investigators with designing the most informative sequencing and analysis strategies at minimal cost. Our specialized customer service provides a connection to the facility and the research.

What Our Collaborators Say

Our research program has benefited tremendously from support we have had from the GTAC. This has included both a wide range of technical services, including quality assessments, library preparation, and sequencing of samples from RNA- and ChIP-Seq experiments, as well as collaborative data analysis support, which, together, has directly contributed in substantive ways to the publications listed below, presentations at national meetings, and ongoing collaborative projects. We are very grateful for and intend to continue utilizing these exceptional resources which have accelerated the advancement of our research program.

Publications That Demonstrate GTAC@MGI’s Service Options
Identification of an epigenetic signature of early mouse liver regeneration that is disrupted by Zn-HDAC inhibition
Postponing the Hypoglycemic Response to Partial Hepatectomy Delays Mouse Liver Regeneration
Diet Modifies Pioglitazone’s Influence on Hepatic PPAR γ-Regulated Mitochondrial Gene Expression

David Rudnick

Associate Professor of Pediatrics

My experience in dealing with GTAC was extremely gratifying. I was able to discuss the study design ahead of time so that I had a sufficient sample size to address my scientific questions. GTAC also helped me work through the best way to analyze and present the large data sets in a simplified format that facilitated my ability to effectively communicate our findings to the scientific community.

Publications That Resulted from GTAC@MGI services
Myocardial B cells are a subset of circulating lymphocytes with delayed transit through the heart
Proteomic Signatures of Heart Failure in Relation to Left Ventricular Ejection Fraction
Developmental changes in myocardial B cells mirror changes in B cells associated with different organs

Douglas Mann

Tobias & Hortense Lewin Professor of Medicine

The Genome Access Technology Center at the McDonnell Genome Institute leads the world and the St. Louis community in the fast-paced, fluid field of genomics. ​ With always versatile offerings of next generation sequencing, microarray, PCR, Bioinformatic services, and other comprehensive options so that can complete our collaborators’ research needs.  In addition to generating high quality genomic, transcriptomic, and even proteomic data, we also perform data analysis and provide technological support to users to ensure maximum data value and understanding of the results.

Featured Technology

Single Cell Multiome ATAC + Gene Expression

Interested in researching the transcriptome and the epigenome in a single cell?  Approach it multidimensionally with the single cell Multiome ATAC + Gene Expression process.  Check out this video to understand it better.