The Genome Technology Access Center

About GTAC

GTAC offers comprehensive Nextgen sequencing, microarray, PCR and Bioinformatic services. In addition to generating high quality genomic, transcriptomic, and even proteomic data, we also perform data analysis and provide technological support to users to ensure maximum data value.  Our goal is to return the highest quality data and, importantly, help researchers make biological sense out of their data.

Acknowledgments

Publications From GTAC Or Where GTAC Is Referenced

  • Shepherd, A. J., Copits, B. A., Mickle, A. D., Karlsson, P., Kadunganattil, S., Haroutounian, S., … Mohapatra, D. P. (2018). Angiotensin II triggers peripheral macrophage-to-sensory neuron redox crosstalk to elicit pain. The Journal of Neuroscience, 38(32), 3517–3542. http://doi.org/10.1523/JNEUROSCI.3542-17.2018
  • Bajpai, G., Schneider, C., Wong, N., Bredemeyer, A., Hulsmans, M., Nahrendorf, M., … Lavine, K. J. (2018). The human heart contains distinct macrophage subsets with divergent origins and functions. Nature Medicine, 24(8), 1234–1245. http://doi.org/10.1038/s41591-018-0059-x
  • Azar, C., Valentine, M., Trausch-Azar, J., Druley, T., Nelson, D. M., & Schwartz, A. L. (2018). RNA-Seq identifies genes whose proteins are transformative in the differentiation of cytotrophoblast to syncytiotrophoblast, in human primary villous and BeWo trophoblasts. Scientific Reports, 8(1). http://doi.org/10.1038/s41598-018-23379-2
  • Keleher, M. R., Zaidi, R., Shah, S., Oakley, M. E., Pavlatos, C., Idrissi, S. El, … Cheverud, J. M. (2018). Maternal high-fat diet associated with altered gene expression, DNA methylation, and obesity risk in mouse offspring. PLoS ONE, 13(2). http://doi.org/10.1371/journal.pone.0192606
  • Lin, J. B., Sene, A., Santeford, A., Fujiwara, H., Sidhu, R., Ligon, M. M., … Apte, R. S. (2018). Oxysterol Signatures Distinguish Age-Related Macular Degeneration from Physiologic Aging. EBioMedicine, 32, 9–20. http://doi.org/10.1016/j.ebiom.2018.05.035
  • Umegaki, Y., Brotons, A. M., Nakanishi, Y., Luo, Z., Zhang, H., Bonni, A., & Ikeuchi, Y. (2018). Palladin Is a Neuron-Specific Translational Target of mTOR Signaling That Regulates Axon Morphogenesis. JOURNAL OF NEUROSCIENCE, 38(21), 4985–4995. http://doi.org/10.1523/JNEUROSCI.2370-17.2018
  • Lee, S. W., Oh, Y. M., Lu, Y.-L., Kim, W. K., & Yoo, A. S. (2018). MicroRNAs Overcome Cell Fate Barrier by Reducing EZH2-Controlled REST Stability during Neuronal Conversion of Human Adult Fibroblasts. DEVELOPMENTAL CELL, 46(1), 73+. http://doi.org/10.1016/j.devcel.2018.06.007
  • Victor, M. B., Richner, M., Olsen, H. E., Lee, S. W., Monteys, A. M., Ma, C., … Yoo, A. S. (2018). Striatal neurons directly converted from Huntington’s disease patient fibroblasts recapitulate age-associated disease phenotypes. NATURE NEUROSCIENCE, 21(3), 341+. http://doi.org/10.1038/s41593-018-0075-7
  • Lin, H., Zhang, Z., Iomini, C., & Dutcher, S. K. (2018). Identifying RNA splicing factors using IFT genes in Chlamydomonas reinhardtii. Open Biology, 8(3). http://doi.org/10.1098/rsob.170211
  • Lin, J. B., Moolani, H. V, Sene, A., Sidhu, R., Kell, P., Lin, J. B., … Apte, R. S. (2018). Macrophage microRNA-150 promotes pathological angiogenesis as seen in age-related macular degeneration. JCI Insight, 3(7), 1–17. http://doi.org/10.1172/jci.insight.120157
  • Kfoury, N., Sun, T., Yu, K., Rockwell, N., Tinkum, K. L., Qi, Z., … Rubin, J. B. (2018). Cooperative p16 and p21 action protects female astrocytes from transformation. Acta Neuropathologica Communications, 6(1), 12. http://doi.org/10.1186/s40478-018-0513-5
  • Bando, J. K., Gilfillan, S., Song, C., McDonald, K. G., Huang, S. C.-C., Newberry, R. D., … Colonna, M. (2018). The Tumor Necrosis Factor Superfamily Member RANKL Suppresses Effector Cytokine Production in Group 3 Innate Lymphoid Cells. IMMUNITY, 48(6), 1208+. http://doi.org/10.1016/j.immuni.2018.04.012
  • Cherian, M. A., Olson, S., Sundaramoorthi, H., Cates, K., Cheng, X., Harding, J., … Rauch, D. (2018). An activating mutation of interferon regulatory factor 4 (IRF4) in adult T-cell leukemia. The Journal of Biological Chemistry, 293(18), 6844–6858. http://doi.org/10.1074/jbc.RA117.000164
  • Williams, M. L. K., Sawada, A., Budine, T., Yin, C., Gontarz, P., & Solnica-Krezel, L. (2018). Gon4l regulates notochord boundary formation and cell polarity underlying axis extension by repressing adhesion genes. NATURE COMMUNICATIONS, 9. http://doi.org/10.1038/s41467-018-03715-w
  • Prusa, J., Jensen, D., Santiago-Collazo, G., Pope, S. S., Garner, A. L., Miller, J. J., … Stallings, C. L. (2018). Domains within RbpA serve specific functional roles that regulate the expression of distinct mycobacterial gene subsets. Journal of Bacteriology, 200(13). http://doi.org/10.1128/JB.00690-17
  • Musselman, L. P., Fink, J. L., Maier, E. J., Gatto, J. A., Brent, M. R., & Baranski, T. J. (2018). Seven-Up Is a Novel Regulator of Insulin Signaling. GENETICS, 208(4), 1643–1656. http://doi.org/10.1534/genetics.118.300770
  • Kramann, R., Schneider, R. K., Benjamin, D., Kramann, R., Machado, F., Wu, H., … Hoeft, K. (2018). Parabiosis and single-cell RNA sequencing reveal a limited contribution of monocytes to myofibroblasts in kidney fibrosis Find the latest version : Parabiosis and single-cell RNA sequencing reveal a limited contribution of monocytes to myofibroblasts in k. Journal of Clinical Investigation Insight, 3(9)(9). http://doi.org/10.1172/JCI.INSIGHT.99561
  • Pan, Y., Xiong, M., Chen, R., Ma, Y., Corman, C., Maricos, M., … Gutmann, D. H. (2018). Athymic mice reveal a requirement for T-cell-microglia interactions in establishing a microenvironment supportive of Nf1 low-grade glioma growth. GENES & DEVELOPMENT, 32(7–8), 491–496. http://doi.org/10.1101/gad.310797.117
  • Fernández, M. V, Budde, J., Del-Aguila, J. L., Ibañez, L., Deming, Y., Harari, O., … Silverman, J. M. (2018). Evaluation of gene-based family-based methods to detect novel genes associated with familial late onset Alzheimer disease. Frontiers in Neuroscience, 12(APR). http://doi.org/10.3389/fnins.2018.00209
  • Andley, U. P., Tycksen, E., McGlasson-Naumann, B. N., & Hamilton, P. D. (2018). Probing the changes in gene expression due to $α$-crystallin mutations in mouse models of hereditary human cataract. PLoS ONE, 13(1). http://doi.org/10.1371/journal.pone.0190817
  • Kim, S., Maynard, J. C., Strickland, A., Burlingame, A. L., & Milbrandt, J. (2018). Schwann cell O-GlcNAcylation promotes peripheral nerve remyelination via attenuation of the AP-1 transcription factor JUN. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115(31), 8019–8024. http://doi.org/10.1073/pnas.1805538115
  • Gonzalez, K. L., Ratzel, S. E., Burks, K. H., Danan, C. H., Wages, J. M., Zolman, B. K., & Bartel, B. (2018). A pex1 missense mutation improves peroxisome function in a subset of Arabidopsis pex6 mutants without restoring PEX5 recycling. Proceedings of the National Academy of Sciences, 115(14), 201721279. http://doi.org/10.1073/pnas.1721279115
  • Song, W. M., Joshita, S., Zhou, Y., Ulland, T. K., Gilfillan, S., & Colonna, M. (2018). Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism. The Journal of Experimental Medicine, 215(3), jem.20171529. http://doi.org/10.1084/jem.20171529
  • Mostafa, H. H., Thompson, T. W., Konen, A. J., Haenchen, S. D., Hilliard, J. G., Macdonald, S. J., … Davido, D. J. (2018). Herpes Simplex Virus 1 Mutant with Point Mutations in UL39 Is Impaired for Acute Viral Replication in Mice, Establishment of Latency, and Explant-Induced Reactivation. Journal of Virology, 92(7), JVI.01654–17. http://doi.org/10.1128/JVI.01654-17
  • Meyer, M. A., Baer, J. M., Knolhoff, B. L., Nywening, T. M., Panni, R. Z., Su, X., … Denardo, D. G. (2018). Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance. Nature Communications, 9(1). http://doi.org/10.1038/s41467-018-03600-6
  • Savage, J. E., Salvatore, J. E., Aliev, F., Edwards, A. C., Hickman, M., Kendler, K. S., … Dick, D. M. (2018). Polygenic Risk Score Prediction of Alcohol Dependence Symptoms Across Population-Based and Clinically Ascertained Samples. Alcoholism: Clinical and Experimental Research, 42(3), 520–530. http://doi.org/10.1111/acer.13589
  • Cruchaga, C., Del-Aguila, J. L., Saef, B., Black, K., Fernandez, M. V., Budde, J., … Study, N.-L. F. (2018). Polygenic risk score of sporadic late-onset Alzheimer’s disease reveals a shared architecture with the familial and early-onset forms. Alzheimers & Dementia, 14(2), 205–214. http://doi.org/10.1016/j.jalz.2017.08.013
  • Gorman, M. J., Caine, E. A., Zaitsev, K., Begley, M. C., Weger-Lucarelli, J., Uccellini, M. B., … Diamond, M. S. (2018, May). An Immunocompetent Mouse Model of Zika Virus Infection. Cell Host and Microbe. 50 HAMPSHIRE ST, FLOOR 5, CAMBRIDGE, MA 02139 USA: CELL PRESS. http://doi.org/10.1016/j.chom.2018.04.003
  • Ostrander, E. L., Koh, W. K., Mallaney, C., Kramer, A. C., Wilson, W. C., Zhang, B., & Challen, G. A. (2018). The GNAS(R201C) mutation associated with clonal hematopoiesis supports transplantable hematopoietic stem cell activity. EXPERIMENTAL HEMATOLOGY, 57, 14–20. http://doi.org/10.1016/j.exphem.2017.09.004
  • Lam, W. Y., Jash, A., Yao, C. H., D’Souza, L., Wong, R., Nunley, R. M., … Bhattacharya, D. (2018, August). Metabolic and Transcriptional Modules Independently Diversify Plasma Cell Lifespan and Function. Cell Reports. 50 HAMPSHIRE ST, FLOOR 5, CAMBRIDGE, MA 02139 USA: CELL PRESS. http://doi.org/10.1016/j.celrep.2018.07.084
  • Gonzalez, K. L., Fleming, W. A., Kao, Y. T., Wright, Z. J., Venkova, S. V, Ventura, M. J., & Bartel, B. (2017). Disparate peroxisome-related defects in Arabidopsis pex6 and pex26 mutants link peroxisomal retrotranslocation and oil body utilization. Plant Journal, 92(1), 110–128. http://doi.org/10.1111/tpj.13641
  • Brähler, S., Zinselmeyer, B. H., Raju, S., Nitschke, M., Suleiman, H., Saunders, B. T., … Shaw, A. S. (2017). Opposing Roles of Dendritic Cell Subsets in Experimental GN. Journal of the American Society of Nephrology : JASN, 29(1), ASN.2017030270. http://doi.org/10.1681/ASN.2017030270
  • Zhong, H., Hu, X., Janowski, A. B., Storch, G. A., Su, L., Cao, L., … Xu, J. (2017). Whole transcriptome profiling reveals major cell types in the cellular immune response against acute and chronic active Epstein-Barr virus infection. SCIENTIFIC REPORTS, 7. http://doi.org/10.1038/s41598-017-18195-Z
  • Zhao, H., & Choi, K. (2017). A CRISPR screen identifies genes controlling Etv2 threshold expression in murine hemangiogenic fate commitment. NATURE COMMUNICATIONS, 8. http://doi.org/10.1038/s41467-017-00667-5
  • Laurent, F., Girdziusaite, A., Gamart, J., Barozzi, I., Osterwalder, M., Akiyama, J. A., … Zeller, R. (2017). HAND2 Target Gene Regulatory Networks Control Atrioventricular Canal and Cardiac Valve Development. CELL REPORTS, 19(8), 1602–1613. http://doi.org/10.1016/j.celrep.2017.05.004
  • Hughes, A. E. O., Enright, J. M., Myers, C. A., Shen, S. Q., & Corbo, J. C. (2017). Cell Type-Specific Epigenomic Analysis Reveals a Uniquely Closed Chromatin Architecture in Mouse Rod Photoreceptors. SCIENTIFIC REPORTS, 7. http://doi.org/10.1038/srep43184
  • Matt, G. Y., & Umen, J. G. (2017). Cell-Type Transcriptomes of the Multicellular Green Alga Volvox carteri Yield Insights into the Evolutionary Origins of Germ and Somatic Differentiation Programs. G3-GENES GENOMES GENETICS, 8(2), g3.300253.2017. http://doi.org/10.1534/g3.117.300253
  • Mahajan, N., Wu, H.-J., Bennett, R. L., Troche, C., Licht, J. D., Weber, J. D., … Tomasson, M. H. (2017). Sabotaging of the oxidative stress response by an oncogenic noncoding RNA. FASEB JOURNAL, 31(2), 482–490. http://doi.org/10.1096/fj.201600654R
  • Oetjen, L. K., Mack, M. R., Feng, J., Whelan, T. M., Niu, H., Guo, C. J., … Kim, B. S. (2017). Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch. CELL, 171(1), 217+. http://doi.org/10.1016/j.cell.2017.08.006
  • McGill, B. E., Barve, R. A., Maloney, S. E., Strickland, A., Rensing, N., Wang, P., … Milbrandt, J. (2017). Abnormal Microglia and Enhanced Inflammation-Related Gene Transcription in Mice with Conditional Deletion of Ctcf in Camk2a-Cre -Expressing Neurons. The Journal of Neuroscience, 38(1), 917–936. http://doi.org/10.1523/JNEUROSCI.0936-17.2017
  • Bradley, A. S., Swanson, P. K., Muller, E. E. L., Bringel, F., Caroll, S. M., Pearson, A., … Marx, C. J. (2017). Hopanoid-free Methylobacterium extorquens DM4 overproduces carotenoids and has widespread growth impairment. PLOS ONE, 12(3). http://doi.org/10.1371/journal.pone.0173323
  • Simms, C. L., Yan, L. L., & Zaher, H. S. (2017). Ribosome Collision Is Critical for Quality Control during No-Go Decay. MOLECULAR CELL, 68(2), 361+. http://doi.org/10.1016/j.molcel.2017.08.019
  • Leung, W., Shaffer, C. D., Chen, E. J., Quisenberry, T. J., Ko, K., Braverman, J. M., … Fac, P. S. (2017). Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element. G3-GENES GENOMES GENETICS, 7(8), 2439–2460. http://doi.org/10.1534/g3.117.040907
  • Rinaldi, M. A., Fleming, W. A., Gonzalez, K. L., Park, J., Ventura, M. J., Patel, A. B., & Bartel, B. (2017). The PEX1 ATPase Stabilizes PEX6 and Plays Essential Roles in Peroxisome Biology. PLANT PHYSIOLOGY, 174(4), 2231–2247. http://doi.org/10.1104/pp.17.00548
  • Shi, Y., He, G., Lee, W.-C., McKenzie, J. A., Silva, M. J., & Long, F. (2017). Gli1 identifies osteogenic progenitors for bone formation and fracture repair. NATURE COMMUNICATIONS, 8. http://doi.org/10.1038/s41467-017-02171-2
  • Patel, S. J., Zhao, G., Penna, V. R., Park, E., Lauron, E. J., Harvey, I. B., … Yokoyama, W. M. (2017). A Murine Herpesvirus Closely Related to Ubiquitous Human Herpesviruses Causes T-Cell Depletion. JOURNAL OF VIROLOGY, 91(9). http://doi.org/10.1128/JVI.02463-16
  • Bin Cho, S., Aliev, F., Clark, S. L., Adkins Amy E. and Edenberg, H. J., Bucholz, K. K., & Porjesz Bernice and Dick, D. M. (2017). Using Patterns of Genetic Association to Elucidate Shared Genetic Etiologies Across Psychiatric Disorders. BEHAVIOR GENETICS, 47(4), 405–415. http://doi.org/10.1007/s10519-017-9844-4
  • Xue, Y., Sato, S., Razafsky, D., Sahu, B., Shen, S. Q., Potter, C., … Kefalov, V. J. (2017). The role of retinol dehydrogenase 10 in the cone visual cycle. SCIENTIFIC REPORTS, 7. http://doi.org/10.1038/s41598-017-02549-8
  • Meganathan, K., Lewis, E. M. A., Gontarz, P., Liu, S., Stanley, E. G., Elefanty, A. G., … Kroll, K. L. (2017). Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development. Proceedings of the National Academy of Sciences, 114(52), E11180–E11189. http://doi.org/10.1073/pnas.1712365115
  • Cortez, V. S., Ulland, T. K., Cervantes-Barragan, L., Bando, J. K., Robinette, M. L., Wang, Q., … Colonna, M. (2017). SMAD4 impedes the conversion of NK cells into ILC1-like cells by curtailing non-canonical TGF-beta signaling. NATURE IMMUNOLOGY, 18(9), 995+. http://doi.org/10.1038/ni.3809
  • Agrawal, A., Chou, Y.-L., Carey, C. E., Baranger, D. A. A., Zhang, B., Sherva, R., … Nelson, E. C. (2017). Genome-wide association study identifies a novel locus for cannabis dependence. Molecular Psychiatry, 23(5), 1293–1302. http://doi.org/10.1038/mp.2017.200
  • Zhu, Y., Herndon, J. M., Sojka, D. K., Kim, K.-W., Knolhoff, B. L., Zuo, C., … DeNardo, D. G. (2017). Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression. IMMUNITY, 47(2), 323+. http://doi.org/10.1016/j.immuni.2017.07.014
  • Liu, X., McKenzie, J. A., Maschhoff, C. W., Gardner, M. J., & Silva, M. J. (2017). Exogenous hedgehog antagonist delays but does not prevent fracture healing in young mice. Bone, 103, 241–251. http://doi.org/10.1016/j.bone.2017.07.017
  • Wilson, M. C., Mutka, A. M., Hummel, A. W., Berry, J., Chauhan, R. D., Vijayaraghavan, A., … Bart, R. S. (2017). Gene expression atlas for the food security crop cassava. New Phytologist, 213(4), 1632–1641. http://doi.org/10.1111/nph.14443
  • Meyers, J. L., Zhang, J., Wang, J. C., Su, J., Kuo, S. I., Kapoor, M., … Porjesz, B. (2017). An endophenotype approach to the genetics of alcohol dependence: A genome wide association study of fast beta EEG in families of African ancestry. Molecular Psychiatry, 22(12), 1767–1775. http://doi.org/10.1038/mp.2016.239
  • Li, J. J., Cho, S. Bin, Salvatore, J. E., Edenberg, H., Agrawal, A., Chorlian, D. B., … Reilly, M. (2017). The Impact of Peer Substance Use and Polygenic Risk on Trajectories of Heavy Episodic Drinking Across Adolescence and Emerging Adulthood. Alcoholism: Clinical and Experimental Research, 41(1), 65–75. http://doi.org/10.1111/acer.13282
  • Li, M. W., Sletten, A. C., Lee, J., Pyles, K. D., Matkovich, S. J., Ory, D. S., & Schaffer, J. E. (2017). Nuclear export factor 3 regulates localization of small nucleolar RNAs. Journal of Biological Chemistry, 292(49), 20228–20239. http://doi.org/10.1074/jbc.M117.818146
  • Ee, X., Yan, Y., Hunter, D. A., Schellhardt, L., Sakiyama-Elbert, S. E., Mackinnon, S. E., & Wood, M. D. (2017). Transgenic SCs expressing GDNF-IRES-DsRed impair nerve regeneration within acellular nerve allografts. Biotechnology and Bioengineering, 114(9), 2121–2130. http://doi.org/10.1002/bit.26335
  • Meyers, J. L., Zhang, J., Manz, N., Rangaswamy, M., Kamarajan, C., Wetherill, L., … Porjesz, B. (2017). A genome wide association study of fast beta EEG in families of European ancestry. International Journal of Psychophysiology, 115(SI), 74–85. http://doi.org/10.1016/j.ijpsycho.2016.12.008
  • Wahlestedt, M., Ladopoulos, V., Hidalgo, I., Sanchez Castillo, M., Hannah, R., Säwén, P., … Bryder, D. (2017). Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor. Cell Reports, 21(8), 2251–2263. http://doi.org/10.1016/j.celrep.2017.10.112
  • Basu, P., Kruse, C. P. S., Luesse, D. R., & Wyatt, S. E. (2017). Growth in spaceflight hardware results in alterations to the transcriptome and proteome. Life Sciences in Space Research, 15, 88–96. http://doi.org/10.1016/j.lssr.2017.09.001
  • Miyoshi, H., VanDussen, K. L., Malvin, N. P., Ryu, S. H., Wang, Y., Sonnek, N. M., … Stappenbeck, T. S. (2017). Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium. The EMBO Journal, 36(1), 5–24. http://doi.org/10.15252/embj.201694660
  • Sanchez, N. E., Harty, B. L., O’Reilly-Pol, T., Ackerman, S. D., Herbert, A. L., Holmgren, M., … Monk, K. R. (2017). Whole Genome Sequencing-Based Mapping and Candidate Identification of Mutations from Fixed Zebrafish Tissue. G3 (Bethesda, Md.), 7(10), g3.300212.2017. http://doi.org/10.1534/g3.117.300212
  • Thompson, R. E., Lake, A., Kenny, P., Saunders, M., Sakers, K., Iyer, N., … Sakiyama-Elbert, S. E. (2017). Different Mixed Astrocyte Populations Derived from Embryonic Stem Cells have Variable Neuronal Growth Support Capacities. Stem Cells and Development, 26(22), scd.2017.0121. http://doi.org/10.1089/scd.2017.0121
  • Ferris, S. T., Zakharov, P. N., Wan, X., Calderon, B., Artyomov, M. N., Unanue, E. R., & Carrero, J. A. (2017). The islet-resident macrophage is in an inflammatory state and senses microbial products in blood. The Journal of Experimental Medicine, 214(8), 2369–2385. http://doi.org/10.1084/jem.20170074
  • Barron, L. K., Bao, J. W., Aladegbami, B. G., Colasanti, J. J., Guo, J., Erwin, C. R., & Warner, B. W. (2017). Toll-like receptor 4 is critical for the development of resection-associated hepatic steatosis. Journal of Pediatric Surgery, 52(6), 1014–1019. http://doi.org/10.1016/j.jpedsurg.2017.03.026
  • Huang, Y., Koues, O. I., yang Zhao, J., Liu, R., Pyfrom, S. C., Payton, J. E., & Oltz, E. M. (2017). cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer Independent. Cell Reports, 18(12), 2918–2931. http://doi.org/10.1016/j.celrep.2017.02.067
  • Zhao, L. J., Loewenstein, P. M., & Green, M. (2017). Adenovirus E1A TRRAP-targeting domain-mediated enhancement of MYC association with the NuA4 complex activates a panel of MYC target genes enriched for gene expression and ribosome biogenesis. Virology, 512, 172–179. http://doi.org/10.1016/j.virol.2017.08.010
  • Reinl, E. L., Goodwin, Z. A., Raghuraman, N., Lee, G. Y., Jo, E. Y., Gezahegn, B. M., … England, S. K. (2017). Novel oxytocin receptor variants in laboring women requiring high doses of oxytocin. American Journal of Obstetrics and Gynecology, 217(2), 214.e1–214.e8. http://doi.org/10.1016/j.ajog.2017.04.036
  • Kruse, C. P. S., Basu, P., Luesse, D. R., & Wyatt, S. E. (2017). Transcriptome and proteome responses in RNAlater preserved tissue of Arabidopsis thaliana. PLoS ONE, 12(4). http://doi.org/10.1371/journal.pone.0175943
  • Zhu, Z., Gorman, M. J., McKenzie, L. D., Chai, J. N., Hubert, C. G., Prager, B. C., … Chheda, M. G. (2017). Zika virus has oncolytic activity against glioblastoma stem cells. The Journal of Experimental Medicine, 214(10), jem.20171093. http://doi.org/10.1084/jem.20171093
  • Kramer, A. C., Kothari, A., Wilson, W. C., Celik, H., Nikitas, J., Mallaney, C., … Challen, G. A. (2017, November). Dnmt3a regulates T-cell development and suppresses T-ALL transformation. Leukemia. MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND: NATURE PUBLISHING GROUP. http://doi.org/10.1038/leu.2017.89
  • Bennett, T. M., M’Hamdi, O., Hejtmancik, J. F., & Shiels, A. (2017). Germ-line and somatic EPHA2 coding variants in lens aging and cataract. PLoS ONE, 12(12). http://doi.org/10.1371/journal.pone.0189881
  • Köster, S., Upadhyay, S., Chandra, P., Papavinasasundaram, K., Yang, G., Hassan, A., … Philips, J. A. (2017). Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA. Proceedings of the National Academy of Sciences, 114(41), 201707792. http://doi.org/10.1073/pnas.1707792114
  • Ho, N. R. Y., Usmani, A. R., Yin, Y., Ma, L., & Conrad, D. F. (2017). Multiplex shRNA Screening of Germ Cell Development by in Vivo Transfection of Mouse Testis. G3 (Bethesda, Md.), 7(1), 247–255. http://doi.org/10.1534/g3.116.036087
  • Hiken, J. F., McDonald, J. I., Decker, K. F., Sanchez, C., Hoog, J., Vanderkraats, N. D., … Edwards, J. R. (2017). Epigenetic activation of the prostaglandin receptor EP4 promotes resistance to endocrine therapy for breast cancer. Oncogene, 36(16), 2319–2327. http://doi.org/10.1038/onc.2016.397
  • Barron, L. K., Warner, B. B., Tarr, P. I., Shannon, W. D., Deych, E., & Warner, B. W. (2017). Independence of gut bacterial content and neonatal necrotizing enterocolitis severity. Journal of Pediatric Surgery, 52(6), 993–998. http://doi.org/10.1016/j.jpedsurg.2017.03.029
  • Dalal, J. S., Yang, C., Sapkota, D., Lake, A. M., O’Brien, D. R., & Dougherty, J. D. (2017). Quantitative Nucleotide Level Analysis of Regulation of Translation in Response to Depolarization of Cultured Neural Cells. Frontiers in Molecular Neuroscience, 10. http://doi.org/10.3389/fnmol.2017.00009
  • Patel, M. D., Mohan, J., Schneider, C., Bajpai, G., Purevjav, E., Canter, C. E., … Lavine, K. J. (2017). Pediatric and adult dilated cardiomyopathy represent distinct pathological entities. JCI Insight, 2(14), 1–16. http://doi.org/10.1172/jci.insight.94382
  • Xiao, Y., Bowen, C. H., Liu, D., & Zhang, F. (2016). Exploiting nongenetic cell-to-cell variation for enhanced biosynthesis. NATURE CHEMICAL BIOLOGY, 12(5), 339+. http://doi.org/10.1038/NCHEMBIO.2046
  • Lim, Y. Y., Hassenstab, J., Cruchaga, C., Goate, A., Fagan, A. M., Benzinger, T. L. S., … Bateman, R. J. (2016). BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer’s disease. Brain, 139(10), 2766–2777. http://doi.org/10.1093/brain/aww200
  • Rai, M. F., Sandell, L. J., Zhang, B., Wright, R. W., & Brophy, R. H. (2016). RNA Microarray Analysis of Macroscopically Normal Articular Cartilage from Knees Undergoing Partial Medial Meniscectomy: Potential Prediction of the Risk for Developing Osteoarthritis. PLOS ONE, 11(5). http://doi.org/10.1371/journal.pone.0155373
  • Zhou, Y., Bennett, T. M., & Shiels, A. (2016). Lens ER-stress response during cataract development in Mip-mutant mice. Biochimica et Biophysica Acta – Molecular Basis of Disease, 1862(8), 1433–1442. http://doi.org/10.1016/j.bbadis.2016.05.003
  • Turkoz, M., Townsend, R. R., & Kopan, R. (2016). The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 136(6), 1106–1115. http://doi.org/10.1016/j.jid.2016.02.018
  • Shen, S. Q., Myers, C. A., Hughes, A. E. O., Byrne, L. C., Flannery, J. G., & Corbo, J. C. (2016). Massively parallel cis-regulatory analysis in the mammalian central nervous system. GENOME RESEARCH, 26(2), 238–255. http://doi.org/10.1101/gr.193789.115
  • Bennett, T. M., Zhou, Y., & Shiels, A. (2016). Lens transcriptome profile during cataract development in Mip-null mice. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 478(2), 988–993. http://doi.org/10.1016/j.bbrc.2016.08.068
  • Pehrsson, E. C., Tsukayama, P., Patel, S., Mejia-Bautista, M., Sosa-Soto, G., Navarrete, K. M., … Dantas, G. (2016). Interconnected microbiomes and resistomes in low-income human habitats. NATURE, 533(7602), 212+. http://doi.org/10.1038/nature17672
  • Lam, W. Y., Becker, A. M., Kennerly, K. M., Wong Rachel and Curtis, J. D., Llufrio, E. M., McCommis Kyle S. and Fahrmann, J., … Bhattacharya, D. (2016). Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells. IMMUNITY, 45(1), 60–73. http://doi.org/10.1016/j.immuni.2016.06.011
  • Rinaldi, M. A., Patel, A. B., Park, J., Lee, K., Strader, L. C., & Bartel, B. (2016). The Roles of beta-Oxidation and Cofactor Homeostasis in Peroxisome Distribution and Function in Arabidopsis thaliana. GENETICS, 204(3), 1089+. http://doi.org/10.1534/genetics.116.193169
  • Druley, T. E., Wang, L., Lin, S. J., Lee, J. H., Zhang, Q., Daw, E. W., … Mayeux Richard and Province, M. A. (2016). Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study. BMC GERIATRICS, 16. http://doi.org/10.1186/s12877-016-0253-y
  • Kao, Y.-T., Fleming, W. A., Ventura, M. J., & Bartel, B. (2016). Genetic Interactions between PEROXIN12 and Other Peroxisome-Associated Ubiquitination Components. PLANT PHYSIOLOGY, 172(3), 1643–1656. http://doi.org/10.1104/pp.16.01211
  • Wu, X., Briseño, C. G., Grajales-Reyes, G. E., Haldar, M., Iwata, A., Kretzer, N. M., … Murphy, K. M. (2016). Transcription factor Zeb2 regulates commitment to plasmacytoid dendritic cell and monocyte fate. Proceedings of the National Academy of Sciences, 113(51), 14775–14780. http://doi.org/10.1073/pnas.1611408114
  • Lee, J., Harris, A. N., Holley, C. L., Mahadevan, J., Pyles, K. D., Lavagnino, Z., … Schaffer, J. E. (2016). Rpl13a small nucleolar RNAs regulate systemic glucose metabolism. JOURNAL OF CLINICAL INVESTIGATION, 126(12), 4616–4625. http://doi.org/10.1172/JCI88069
  • Monaco, C. L., Gootenberg, D. B., Zhao, G., Handley, S. A., Ghebremichael, M. S., Lim, E. S., … Virgin, H. W. (2016). Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome. CELL HOST & MICROBE, 19(3), 311–322. http://doi.org/10.1016/j.chom.2016.02.011
  • Chartier, K. G., Dick, D. M., Almasy, L., Chan, G., Aliev, F., Schuckit, M. A., … Hesselbrock, V. M. (2016). Interactions Between Alcohol Metabolism Genes and Religious Involvement in Association With Maximum Drinks and Alcohol Dependence Symptoms. JOURNAL OF STUDIES ON ALCOHOL AND DRUGS, 77(3), 393–404.
  • Huang, J., Schriefer, A. E., Cliften, P. F., Dietzen, D., Kulkarni, S., Sing, S., … Rudnick, D. A. (2016). Postponing the hypoglycemic response to partial hepatectomy delays mouse liver regeneration. American Journal of Pathology, 186(3), 587–599. http://doi.org/10.1016/j.ajpath.2015.10.027
  • Carey, C. E., Agrawal, A., Bucholz, K. K., Hartz, S. M., Lynskey, M. T., Nelson, E. C., … Bogdan, R. (2016). Associations between Polygenic Risk for Psychiatric Disorders and Substance Involvement. FRONTIERS IN GENETICS, 7. http://doi.org/10.3389/fgene.2016.00149
  • Guggisberg, A. M., Sundararaman, S. A., Lanaspa, M., Moraleda, C., Gonzlez, R., Mayor, A., … Odom, A. R. (2016). Whole-Genome Sequencing to Evaluate the Resistance Landscape Following Antimalarial Treatment Failure With Fosmidomycin-Clindamycin. JOURNAL OF INFECTIOUS DISEASES, 214(7), 1085–1091. http://doi.org/10.1093/infdis/jiw304
  • Morris, E. M., Meers, G. M. E., Koch, L. G., Britton, S. L., Fletcher, J. A., Fu, X., … Thyfault, J. P. (2016). Aerobic capacity and hepatic mitochondrial lipid oxidation alters susceptibility for chronic high-fat diet-induced hepatic steatosis. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 311(4), E749–E760. http://doi.org/10.1152/ajpendo.00178.2016
  • Houghton, J. L., Foustoukos, D. I., Flynn, T. M., Vetriani C. and Bradley, A. S., & Fike, D. A. (2016). Thiosulfate oxidation by Thiomicrospira thermophila: metabolic flexibility in response to ambient geochemistry. ENVIRONMENTAL MICROBIOLOGY, 18(9, SI), 3057–3072. http://doi.org/10.1111/1462-2920.13232
  • Wilfert, A. B., Chao, K. R., Kaushal, M., Jain, S., Zollner, S., Adams, D. R., & Conrad, D. F. (2016). Genome-wide significance testing of variation from single case exomes. NATURE GENETICS, 48(12), 1455–1461. http://doi.org/10.1038/ng.3697
  • Wu, D., Sanin, D. E., Everts, B., Chen, Q., Qiu, J., Buck, M. D., … Pearce, E. J. (2016). Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function. IMMUNITY, 44(6), 1325–1336. http://doi.org/10.1016/j.immuni.2016.06.006
  • Mesa, R., Tyagi, M., Harocopos, G., & Vollman David and Bassnett, S. (2016). Somatic Variants in the Human Lens Epithelium: A Preliminary Assessment. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 57(10), 4063–4075. http://doi.org/10.1167/iovs.16-19726
  • Koues, O. I., Collins, P. L., Cella, M., Robinette, M. L., Porter, S. I., Pyfrom, S. C., … Oltz, E. M. (2016). Distinct Gene Regulatory Pathways for Human Innate versus Adaptive Lymphoid Cells. CELL, 165(5), 1134–1146. http://doi.org/10.1016/j.cell.2016.04.014
  • Wu, X., Briseno, C. G., Durai, V., Albring Joern C. and Haldar, M., Bagadia, P., Kim, K.-W., … Murphy, K. M. (2016). Mafb lineage tracing to distinguish macrophages from other immune lineages reveals dual identity of Langerhans cells. JOURNAL OF EXPERIMENTAL MEDICINE, 213(12), 2553–2565. http://doi.org/10.1084/jem.20160600
  • Gu, J., Stevens, M., Xing, X., Li, D., Zhang, B., Payton, J. E., … Wang, T. (2016). Mapping of Variable DNA Methylation Across Multiple Cell Types Defines a Dynamic Regulatory Landscape of the Human Genome. G3-GENES GENOMES GENETICS, 6(4), 973–986. http://doi.org/10.1534/g3.115.025437
  • Kramann, R., Goettsch, C., Wongboonsin, J., Iwata, H., Schneider, R. K., Kuppe, C., … Humphreys, B. D. (2016). Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease. Cell Stem Cell, 19(5), 628–642. http://doi.org/10.1016/j.stem.2016.08.001
  • Reese, T. A., Bi, K., Kambal, A., Filali-Mouhim, A., Beura, L. K., Burger, M. C., … Virgin, H. W. (2016). Sequential Infection with Common Pathogens Promotes Human-like Immune Gene Expression and Altered Vaccine Response. CELL HOST & MICROBE, 19(5), 713–719. http://doi.org/10.1016/j.chom.2016.04.003
  • Gujar, A. D., Le, S., Mao, D. D., Dadey, D. Y. A., Turski, A., Sasaki, Y., … Kim, A. H. (2016). An NAD + -dependent transcriptional program governs self-renewal and radiation resistance in glioblastoma. Proceedings of the National Academy of Sciences, 113(51), E8247–E8256. http://doi.org/10.1073/pnas.1610921114
  • Brettmann, E. A., Shaik, J. S., Zangger, H., Lye, L.-F., Kuhlmann, F. M., Akopyants, N. S., … Beverley, S. M. (2016). Tilting the balance between RNA interference and replication eradicates Leishmania RNA virus 1 and mitigates the inflammatory response. Proceedings of the National Academy of Sciences, 113(43), 11998–12005. http://doi.org/10.1073/pnas.1615085113
  • Yang, Y., Yamada, T., Hill, K. K., Hemberg, M., Reddy, N. C., Cho, H. Y., … Bonni, A. (2016). Chromatin remodeling inactivates Activity genes and regulates neural coding. Science, 353(6296), 300–306. http://doi.org/10.1126/science.aad4225
  • Yu, J., Cliften, P. F., Juehne, T. I., Sinnwell, T. M., Sawyer, C. S., Sharma, M., … Head, R. D. (2015). Multi-platform assessment of transcriptional profiling technologies utilizing a precise probe mapping methodology. BMC Genomics, 16(1). http://doi.org/10.1186/s12864-015-1913-6
  • Enright, J. M., Toomey, M. B., Sato, S. Y., Temple, S. E., Allen, J. R., Fujiwara, R., … Corbo, J. C. (2015). Cyp27c1 red-shifts the spectral sensitivity of photoreceptors by converting Vitamin A1into A2. Current Biology, 25(23), 3048–3057. http://doi.org/10.1016/j.cub.2015.10.018
  • Okeyo-Owuor, T., White, B. S., Chatrikhi, R., Mohan, D. R., Kim, S., Griffith, M., … Graubert, T. A. (2015). U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing. LEUKEMIA, 29(4), 909–917. http://doi.org/10.1038/leu.2014.303
  • Krysiak, K., Tibbitts, J. F., Shao, J., Liu, T., Ndonwi, M., & Walter, M. J. (2015). Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells. Experimental Hematology, 43(4), 319–330. http://doi.org/10.1016/j.exphem.2014.12.005
  • Lin, H., Zhang, Z., Guo, S., Chen, F., Kessler, J. M., Wang, Y. M., & Dutcher, S. K. (2015). A NIMA-Related Kinase Suppresses the Flagellar Instability Associated with the Loss of Multiple Axonemal Structures. PLOS GENETICS, 11(9). http://doi.org/10.1371/journal.pgen.1005508
  • Koues, O. I., Kowalewski, R. A., Chang, L.-W., Pyfrom, S. C., Schmidt, J. A., Luo, H., … Oltz, E. M. (2015). Enhancer Sequence Variants and Transcription-Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B-Cell Lymphoma. IMMUNITY, 42(1), 186–198. http://doi.org/10.1016/j.immuni.2014.12.021
  • Luesse, D. R., Wilson, M. E., & Haswell, E. S. (2015). RNA Sequencing Analysis of the msl2msl3, crl, and ggps1 Mutants Indicates that Diverse Sources of Plastid Dysfunction Do Not Alter Leaf Morphology Through a Common Signaling Pathway. FRONTIERS IN PLANT SCIENCE, 6. http://doi.org/10.3389/fpls.2015.01148
  • Norman, J. M., Handley, S. A., Baldridge, M. T., Droit, L., Liu, C. Y., Keller, B. C., … Virgin, H. W. (2015). Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease. CELL, 160(3), 447–460. http://doi.org/10.1016/j.cell.2015.01.002
  • Milner, J. D., Vogel, T. P., Forbes, L., Ma Chi A. and Stray-Pedersen, A., Niemela, J. E., Lyons Jonathan J. and Engelhardt, K. R., … Cooper, M. A. (2015). Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations. BLOOD, 125(4), 591–599. http://doi.org/10.1182/blood-2014-09-602763
  • Cantoni, C., Bollman, B., Licastro, D., Xie, M., Mikesell, R., Schmidt, R., … Piccio, L. (2015). TREM2 regulates microglial cell activation in response to demyelination in vivo. Acta Neuropathologica, 129(3), 429–447. http://doi.org/10.1007/s00401-015-1388-1
  • Jin, S. C., Carrasquillo, M. M., Benitez, B. A., Skorupa, T., Carrell, D., Patel, D., … Ertekin-Taner, N. (2015). TREM2 is associated with increased risk for Alzheimer’s disease in African Americans. Molecular Neurodegeneration, 10(1). http://doi.org/10.1186/s13024-015-0016-9
  • Xue, Y., Shen, S. Q., Corbo, J. C., & Kefalov, V. J. (2015). Circadian and light-driven regulation of rod dark adaptation. SCIENTIFIC REPORTS, 5. http://doi.org/10.1038/srep17616
  • Collins, P. L., Kyle, K. E., Egawa, T., Shinkai, Y., & Oltz, E. M. (2015). The histone methyltransferase SETDB1 represses endogenous and exogenous retroviruses in B lymphocytes. Proceedings of the National Academy of Sciences, 112(27), 8367–8372. http://doi.org/10.1073/pnas.1422187112
  • Holley, C. L., Li, M. W., Scruggs, B. S., Matkovich, S. J., Ory, D. S., & Schaffer, J. E. (2015). Cytosolic Accumulation of Small Nucleolar RNAs (snoRNAs) Is Dynamically Regulated by NADPH Oxidase. JOURNAL OF BIOLOGICAL CHEMISTRY, 290(18), 11741–11748. http://doi.org/10.1074/jbc.M115.637413
  • Cady, J., Allred, P., Bali, T., Pestronk, A., Goate, A., Miller, T. M., … Baloh, R. H. (2015). Amyotrophic Lateral Sclerosis Onset Is Influenced by the Burden of Rare Variants in Known Amyotrophic Lateral Sclerosis Genes. ANNALS OF NEUROLOGY, 77(1), 100–113. http://doi.org/10.1002/ana.24306
  • Nikolskiy, I., Conrad, D. F., Chun, S., Fay, J. C., Cheverud, J. M., & Lawson, H. A. (2015). Using whole-genome sequences of the LG/J and SM/J inbred mouse strains to prioritize quantitative trait genes and nucleotides. BMC GENOMICS, 16. http://doi.org/10.1186/s12864-015-1592-3
  • Poliani, P. L., Wang, Y., Fontana, E., Robinette, M. L., Yamanish, Y., Gilfillan, S., & Colonna, M. (2015). TREM2 sustains microglial expansion during aging and response to demyelination. JOURNAL OF CLINICAL INVESTIGATION, 125(5), 2161–2170. http://doi.org/10.1172/JCI77983
  • Majumder, K., Rupp, L. J., Yang-Iott, K. S., Koues, O. I., Kyle, K. E., Bassing, C. H., & Oltz, E. M. (2015). Domain-Specific and Stage-Intrinsic Changes in TcrbConformation during Thymocyte Development. The Journal of Immunology, 195(3), 1262–1272. http://doi.org/10.4049/jimmunol.1500692
  • Ocvirk, S., Sava, I. G., Lengfelder, I., Lagkouvardos, I., Steck, N., Roh, J. H., … Haller, D. (2015). Surface-Associated Lipoproteins Link Enterococcus faecalis Virulence to Colitogenic Activity in IL-10-Deficient Mice Independent of Their Expression Levels. PLOS PATHOGENS, 11(6). http://doi.org/10.1371/journal.ppat.1004911
  • Coelho, C., Oliveira Souza, A. C., Derengowski, L. da S., de Leon-Rodriguez, C., Wang, B., Leon-Rivera, R., … Casadevall, A. (2015). Macrophage Mitochondrial and Stress Response to Ingestion of Cryptococcus neoformans. JOURNAL OF IMMUNOLOGY, 194(5), 2345–2357. http://doi.org/10.4049/jimmunol.1402350
  • Enders, T. A., Oh, S., Yang, Z., Montgomery, B. L., & Strader, L. C. (2015). Genome Sequencing of Arabidopsis abp1-5Reveals Second-Site Mutations That May Affect Phenotypes. The Plant Cell, 27(7), 1820–1826. http://doi.org/10.1105/tpc.15.00214
  • Salvatore, J. E., Edwards, A. C., McClintick, J. N., Bigdeli, T. B., Adkins, A., Aliev, F., … Dick, D. M. (2015). Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior. TRANSLATIONAL PSYCHIATRY, 5. http://doi.org/10.1038/tp.2015.36
  • Labos, C., Martinez, S. C., Wang, R. H. L., Lenzini, P. A., Pilote, L., Bogaty, P., … Thanassoulis, G. (2015). Utility of a genetic risk score to predict recurrent cardiovascular events 1 year after an acute coronary syndrome: A pooled analysis of the RISCA, PRAXY, and TRIUMPH cohorts. ATHEROSCLEROSIS, 242(1), 261–267. http://doi.org/10.1016/j.atherosclerosis.2015.07.029
  • Warrington, N. M., Sun, T., Luo, J., McKinstry, R. C., Parkin, P. C., Ganzhorn, S., … Rubin, J. B. (2015). The cyclic AMP pathway is a sex-specific modifier of glioma risk in type I neurofibromatosis patients. Cancer Research, 75(1), 16–21. http://doi.org/10.1158/0008-5472.CAN-14-1891
  • Tinkum, K. L., Stemler, K. M., White, L. S., Loza, A. J., Jeter-Jones, S., Michalski, B. M., … Piwnica-Worms, H. (2015). Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell survival. Proceedings of the National Academy of Sciences, 112(51), 201509249. http://doi.org/10.1073/pnas.1509249112
  • Valdivia, H. O., Reis-Cunha, J. L., Rodrigues-Luiz, G. F., Baptista, R. P., Baldeviano, G. C., Gerbasi, R. V, … Bartholomeu, D. C. (2015). Comparative genomic analysis of Leishmania (Viannia) peruviana and Leishmania (Viannia) braziliensis. BMC GENOMICS, 16. http://doi.org/10.1186/s12864-015-1928-z
  • Forsberg, K. J., Patel, S., Wencewicz, T. A., & Dantas, G. (2015). The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes. CHEMISTRY & BIOLOGY, 22(7), 888–897. http://doi.org/10.1016/j.chembiol.2015.05.017
  • Salvatore, J. E., Aliev, F., Bucholz, K., Agrawal, A., Hesselbrock, V., Hesselbrock, M., … Dick, D. M. (2015). Polygenic Risk for Externalizing Disorders: Gene-by-Development and Gene-by-Environment Effects in Adolescents and Young Adults. CLINICAL PSYCHOLOGICAL SCIENCE, 3(2), 189–201. http://doi.org/10.1177/2167702614534211
  • Mackay, D. S., Bennett, T. M., & Shiels, A. (2015). Exome Sequencing Identifies a Missense Variant in EFEMP1 Co-Segregating in a Family with Autosomal Dominant Primary Open-Angle Glaucoma. PLOS ONE, 10(7). http://doi.org/10.1371/journal.pone.0132529
  • Wang, Y., Cella, M., Mallinson, K., Ulrich, J. D., Young, K. L., Robinette, M. L., … Colonna, M. (2015). TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model. CELL, 160(6), 1061–1071. http://doi.org/10.1016/j.cell.2015.01.049
  • Kharasch, E. D., Regina, K. J., Blood, J., & Friedel, C. (2015). Methadone Pharmacogenetics. ANESTHESIOLOGY, 123(5), 1142–1153. http://doi.org/10.1097/ALN.0000000000000867
  • Harty, B. L., Krishnan, A., Sanchez, N. E., Schioeth, H. B., & Monk, K. R. (2015). Defining the gene repertoire and spatiotemporal expression profiles of adhesion G protein-coupled receptors in zebrafish. BMC GENOMICS, 16. http://doi.org/10.1186/s12864-015-1296-8
  • Ouwenga, R. L., & Dougherty, J. (2015). Fmrp targets or not: long, highly brain-expressed genes tend to be implicated in autism and brain disorders. MOLECULAR AUTISM, 6. http://doi.org/10.1186/s13229-015-0008-1
  • Chalivendra, V., Kanchi, K. L., Onken, M. D., Winkler, A. E., Mardis, E., & Uppaluri, R. (2015). Genomic analysis to define molecular basis of aggressiveness in a mouse model of oral cancer. Genomics Data, 3, 61–62. http://doi.org/10.1016/j.gdata.2014.11.006
  • Valentine, M. C., Linabery, A. M., Chasnoff, S., Hughes, A. E. O., Mallaney, C., Sanchez, N., … Druley, T. E. (2014). Excess congenital non-synonymous variation in leukemia-associated genes in MLL- Infant leukemia: A Children’s Oncology Group report. Leukemia, 28(6), 1235–1241. http://doi.org/10.1038/leu.2013.367
  • Zhang, Z., Fye, S., Borecki, I. B., & Rader, J. S. (2014). Polymorphisms in immune mediators associate with risk of cervical cancer. GYNECOLOGIC ONCOLOGY, 135(1), 69–73. http://doi.org/10.1016/j.ygyno.2014.07.106
  • Jain, S., Noordam, M. J., Hoshi, M., Vallania, F. L., & Conrad, D. F. (2014). Validating single-cell genomics for the study of renal development. Kidney International, 86(5), 1049–1055. http://doi.org/10.1038/ki.2014.104
  • Tripathi, P., Wang, Y., Coussens, M., Manda, K. R., Casey, A. M., Lin, C., … Chen, F. (2014). Activation of NFAT signaling establishes a tumorigenic microenvironment through cell autonomous and non-cell autonomous mechanisms. Oncogene, 33(14), 1840–1849. http://doi.org/10.1038/onc.2013.132
  • Jin, S. C., Benitez, B. A., Karch, C. M., Cooper, B., Skorupa, T., Carrell, D., … Cruchaga, C. (2014). Coding variants in TREM2 increase risk for Alzheimer’s disease. HUMAN MOLECULAR GENETICS, 23(21), 5838–5846. http://doi.org/10.1093/hmg/ddu277
  • Thole, J. M., Beisner, E. R., Liu, J., Venkova, S. V, & Strader, L. C. (2014). Abscisic Acid Regulates Root Elongation Through the Activities of Auxin and Ethylene in Arabidopsis thaliana. G3-GENES GENOMES GENETICS, 4(7), 1259–1274. http://doi.org/10.1534/g3.114.011080
  • Cruz-Orengo, L., Daniels, B. P., Dorsey, D., Basak, S. A., Grajales-Reyes, J. G., McCandless, E. E., … Klein, R. S. (2014). Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility. JOURNAL OF CLINICAL INVESTIGATION, 124(6), 2571–2584. http://doi.org/10.1172/JCI73408
  • Oh, I. Y., Albea, D. M., Goodwin, Z. A., Quiggle, A. M., Baker, B. P., Guggisberg, A. M., … Strong, C. de G. (2014). Regulation of the Dynamic Chromatin Architecture of the Epidermal Differentiation Complex Is Mediated by a c-Jun/AP-1-Modulated Enhancer. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 134(9), 2371–2380. http://doi.org/10.1038/jid.2014.44
  • Forsberg, K. J., Patel, S., Gibson, M. K., Lauber, C. L., Knight, R., Fierer, N., & Dantas, G. (2014). Bacterial phylogeny structures soil resistomes across habitats. NATURE, 509(7502), 612+. http://doi.org/10.1038/nature13377
  • Yamada, T., Yang, Y., Hemberg, M., Yoshida Toshimi and Cho, H. Y., Murphy, J. P., Fioravante, D., … Bonni, A. (2014). Promoter Decommissioning by the NuRD Chromatin Remodeling Complex Triggers Synaptic Connectivity in the Mammalian Brain. NEURON, 83(1), 122–134. http://doi.org/10.1016/j.neuron.2014.05.039
  • Beirowski, B., Babetto, E., Golden, J. P., Chen, Y.-J., Yang, K., Gross, R. W., … Milbrandt, J. (2014). Metabolic regulator LKB1 is crucial for Schwann cell-mediated axon maintenance. NATURE NEUROSCIENCE, 17(10), 1351–1361. http://doi.org/10.1038/nn.3809
  • Mallaney, C., Kothari, A., Martens, A., & Challen, G. A. (2014). Clonal-level responses of functionally distinct hematopoietic stem cells to trophic factors. EXPERIMENTAL HEMATOLOGY, 42(4), 317–327. http://doi.org/10.1016/j.exphem.2013.11.015
  • Victor, M. B., Richner, M., Hermanstyne, T. O., Ransdell, J. L., Sobieski, C., Deng, P.-Y., … Yoo, A. S. (2014). Generation of Human Striatal Neurons by MicroRNA-Dependent Direct Conversion of Fibroblasts. NEURON, 84(2), 311–323. http://doi.org/10.1016/j.neuron.2014.10.016
  • Donlin, M. J., Upadhya, R., Gerik, K. J., Lam, W., Vanarendonk, L. G., Specht, C. A., … Lodge, J. K. (2014). Cross talk between the cell wall integrity and cyclic AMP/protein kinase a pathways in Cryptococcus neoformans. MBio, 5(4). http://doi.org/10.1128/mBio.01573-14
  • Cortez, V. S., Cervantes-Barragan, L., Song, C., Gilfillan, S., McDonald, K. G., Tussiwand, R., … Colonna, M. (2014). CRTAM controls residency of gut CD4 + CD8 + T cells in the steady state and maintenance of gut CD4 + Th17 during parasitic infection. The Journal of Experimental Medicine, 211(4), 623–633. http://doi.org/10.1084/jem.20130904
  • Spencer, D. H., Tyagi, M., Vallania, F., Bredemeyer, A. J., Pfeifer, J. D., Mitra, R. D., & Duncavage, E. J. (2014). Performance of common analysis methods for detecting low-frequency single nucleotide variants in targeted next-generation sequence data. Journal of Molecular Diagnostics, 16(1), 75–88. http://doi.org/10.1016/j.jmoldx.2013.09.003
  • Wang, Y., & Bhattacharya, D. (2014). Adjuvant-specific regulation of long-term antibody responses by ZBTB20. The Journal of Experimental Medicine, 211(5), 841–856. http://doi.org/10.1084/jem.20131821
  • Zhu, Y., Knolhoff, B. L., Meyer, M. A., Nywening, T. M., West, B. L., Luo, J., … De Nardo, D. G. (2014). CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models. Cancer Research, 74(18), 5057–5069. http://doi.org/10.1158/0008-5472.CAN-13-3723
  • Rasmussen, A. A., Kandasamy, D., Beck, H., Crosby, S. D., Björnberg, O., Schnackerz, K. D., & Piškur, J. (2014). Global expression analysis of the yeast Lachancea (saccharomyces) kluyveri reveals new URC genes involved in pyrimidine catabolism. Eukaryotic Cell, 13(1), 31–42. http://doi.org/10.1128/EC.00202-13
  • Gago-Lopez, N., Awaji, O., Zhang, Y., Ko, C., Nsair, A., Liem, D., … MacLellan, W. R. (2014). THY-I Receptor Expression Differentiates Cardiosphere-Derived Cells with Divergent Cardiogenic Differentiation Potential. STEM CELL REPORTS, 2(5), 576–591. http://doi.org/10.1016/j.stemcr.2014.03.003
  • Karnes, H. E., Duncavage, E. J., & Bernadt, C. T. (2014). Targeted next-generation sequencing using fine-needle aspirates from adenocarcinomas of the lung. Cancer Cytopathology, 122(2), 104–113. http://doi.org/10.1002/cncy.21361
  • Ugale, A., Norddahl, G. L., Wahlestedt, M., Sawen, P., Jaako, P., Pronk, C. J., … Bryder, D. (2014). Hematopoietic Stem Cells Are Intrinsically Protected against MLL-ENL-Mediated Transformation. CELL REPORTS, 9(4), 1246–1255. http://doi.org/10.1016/j.celrep.2014.10.036
  • Mackay, D. S., Bennett, T. M., Culican, S. M., & Shiels, A. (2014). Exome sequencing identifies novel and recurrent mutations in GJA8 and CRYGD associated with inherited cataract. HUMAN GENOMICS, 8. http://doi.org/10.1186/s40246-014-0019-6
  • Zhou, D., Zhang, Z., He, L.-M., Du, J., Zhang, F., Sun, C.-K., … Yang, Q. (2014). Conversion of Fibroblasts to Neural Cells by p53 Depletion. CELL REPORTS, 9(6), 2034–2042. http://doi.org/10.1016/j.celrep.2014.11.040
  • Shen, S. Q., Turro, E., & Corbo, J. C. (2014). Hybrid Mice Reveal Parent-of-Origin and Cis- and Trans-Regulatory Effects in the Retina. PLOS ONE, 9(10). http://doi.org/10.1371/journal.pone.0109382
  • Buchan, J. G., Alvarado, D. M., Haller, G., Aferol, H., Miller, N. H., Dobbs, M. B., & Gurnett, C. A. (2014). Are Copy Number Variants Associated With Adolescent Idiopathic Scoliosis? CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 472(10), 3216–3225. http://doi.org/10.1007/s11999-014-3766-8
  • Canny, S. P., Goel, G., Reese, T. A., Zhang, X., Xavier, R., & Virgin, H. W. (2014). Latent Gammaherpesvirus 68 Infection Induces Distinct Transcriptional Changes in Different Organs. Journal of Virology, 88(1), 730–738. http://doi.org/10.1128/JVI.02708-13
  • Blanc, V., Park, E., Schaefer, S., Miller, M., Lin, Y., Kennedy, S., … Davidson, N. O. (2014). Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver. Genome Biology, 15(6). http://doi.org/10.1186/gb-2014-15-6-r79
  • Brace, E. J., Wu, C., Valakh, V., & DiAntonio, A. (2014). SkpA Restrains Synaptic Terminal Growth during Development and Promotes Axonal Degeneration following Injury. JOURNAL OF NEUROSCIENCE, 34(25), 8398–8410. http://doi.org/10.1523/JNEUROSCI.4715-13.2014
  • Reese, T. A., Wakeman, B. S., Choi, H. S., Hufford, M. M., Huang, S. C., Zhang, X., … Virgin, H. W. (2014). Helminth infection reactivates latent gamma-herpesvirus via cytokine competition at a viral promoter. SCIENCE, 345(6196), 573–577. http://doi.org/10.1126/science.1254517
  • Bien-Willner, G. A., & Mitra, R. D. (2014). Mutation and expression analysis in medulloblastoma yields prognostic variants and a putative mechanism of disease for i17q tumors. ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2. http://doi.org/10.1186/s40478-014-0074-1
  • Sudarsanam, P., & Cohen, B. A. (2014). Single Nucleotide Variants in Transcription Factors Associate More Tightly with Phenotype than with Gene Expression. PLoS Genetics, 10(5). http://doi.org/10.1371/journal.pgen.1004325
  • Onken, M. D., Winkler, A. E., Kanchi, K. L., Chalivendra, V., Law, J. H., Rickert, C. G., … Uppaluri, R. (2014). A surprising cross-species conservation in the genomic landscape of mouse and human oral cancer identifies a transcriptional signature predicting metastatic disease. Clinical Cancer Research, 20(11), 2873–2884. http://doi.org/10.1158/1078-0432.CCR-14-0205
  • Khan, A., Shaik, J. S., Behnke, M., Wang, Q., Dubey, J. P., Lorenzi, H. A., … Sibley, L. D. (2014). NextGen sequencing reveals short double crossovers contribute disproportionately to genetic diversity in Toxoplasma gondii. BMC GENOMICS, 15. http://doi.org/10.1186/1471-2164-15-1168
  • Viader, A., Sasaki, Y., Kim, S., Strickland, A., Workman, C. S., Yang, K., … Milbrandt, J. (2013). Aberrant schwann cell lipid metabolism linked to mitochondrial deficits leads to axon degeneration and neuropathy. Neuron, 77(5), 886–898. http://doi.org/10.1016/j.neuron.2013.01.012
  • Spencer, D. H., Sehn, J. K., Abel, H. J., Watson, M. A., Pfeifer, J. D., & Duncavage, E. J. (2013). Comparison of clinical targeted next-generation sequence data from formalin-fixed and fresh-frozen tissue specimens. Journal of Molecular Diagnostics, 15(5), 623–633. http://doi.org/10.1016/j.jmoldx.2013.05.004
  • Ahn, S.-Y., Kim, Y., Kim, S. T., Swat, W., & Miner, J. H. (2013). Scaffolding Proteins DLG1 and CASK Cooperate to Maintain the Nephron Progenitor Population during Kidney Development. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 24(7), 1127–1138. http://doi.org/10.1681/ASN.2012111074
  • Chapa, T. J., Johnson, L. S., Affolter, C., Valentine, M. C., Fehr, A. R., Yokoyama, W. M., & Yu, D. (2013). Murine Cytomegalovirus Protein pM79 Is a Key Regulator for Viral Late Transcription. Journal of Virology, 87(16), 9135–9147. http://doi.org/10.1128/JVI.00688-13
  • Hudson, J., Duncavage, E., Tamburrino, A., Salerno, P., Xi, L., Raffeld, M., … Chernock, R. D. (2013). Overexpression of miR-10a and miR-375 and downregulation of YAP1 in medullary thyroid carcinoma. Experimental and Molecular Pathology, 95(1), 62–67. http://doi.org/10.1016/j.yexmp.2013.05.001
  • Gopalakrishnan, S., Majumder, K., Predeus, A., Huang, Y., Koues, O. I., Verma-Gaur, J., … Oltz, E. M. (2013). Unifying model for molecular determinants of the preselection V$β$ repertoire. Proceedings of the National Academy of Sciences, 110(34), E3206–E3215. http://doi.org/10.1073/pnas.1304048110
  • Matatall, K. A., Agapova, O. A., Onken, M. D., Worley, L. A., Bowcock, A. M., & Harbour, J. W. (2013). BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma. BMC Cancer, 13. http://doi.org/10.1186/1471-2407-13-371
  • Hennig, A. K., Peng, G. H., & Chen, S. (2013). Transcription Coactivators p300 and CBP Are Necessary for Photoreceptor-Specific Chromatin Organization and Gene Expression. PLoS ONE, 8(7). http://doi.org/10.1371/journal.pone.0069721
  • Martel, C., Li, W., Fulp, B., Platt, A. M., Gautier, E. L., Westerterp, M., … Randolph, G. J. (2013). Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice. Journal of Clinical Investigation, 123(4), 1571–1579. http://doi.org/10.1172/JCI63685
  • Harms, M. B., Cady, J., Zaidman, C., Cooper, P., Bali, T., Allred, P., … Baloh, R. H. (2013). Lack of C9ORF72 coding mutations supports a gain of function for repeat expansions in amyotrophic lateral sclerosis. NEUROBIOLOGY OF AGING, 34(9). http://doi.org/10.1016/j.neurobiolaging.2013.03.006
  • Farmer, L. M., Rinaldi, M. A., Young, P. G., Danan, C. H., Burkhart, S. E., & Bartel, B. (2013). Disrupting Autophagy Restores Peroxisome Function to an Arabidopsis lon2 Mutant and Reveals a Role for the LON2 Protease in Peroxisomal Matrix Protein Degradation. The Plant Cell, 25(10), 4085–4100. http://doi.org/10.1105/tpc.113.113407
  • Wolf, L., Harrison, W., Huang, J., Xie, Q., Xiao, N., Sun, J., … Cvekl, A. (2013). Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300. NUCLEIC ACIDS RESEARCH, 41(22), 10199–10214. http://doi.org/10.1093/nar/gkt824
  • Alford, L. M., Mattheyses, A. L., Hunter, E. L., Lin, H., Dutcher, S. K., & Sale, W. S. (2013). The Chlamydomonas mutant pf27 reveals novel features of ciliary radial spoke assembly. Cytoskeleton, 70(12), 804–818. http://doi.org/10.1002/cm.21144
  • Cho, Y., Sloutsky, R., Naegle, K. M., & Cavalli, V. (2013). Injury-Induced HDAC5 Nuclear Export Is Essential for Axon Regeneration. CELL, 155(4), 894–908. http://doi.org/10.1016/j.cell.2013.10.004
  • Carlisle, P. L., & Kadosh, D. (2013). A genome-wide transcriptional analysis of morphology determination in Candida albicans. MOLECULAR BIOLOGY OF THE CELL, 24(3), 246–260. http://doi.org/10.1091/mbc.E12-01-0065
  • Rai, M. F., Schmidt, E. J., McAlinden, A., Cheverud, J. M., & Sandell, L. J. (2013). Molecular Insight into the Association Between Cartilage Regeneration and Ear Wound Healing in Genetic Mouse Models: Targeting New Genes in Regeneration. G3-GENES GENOMES GENETICS, 3(11), 1881–1891. http://doi.org/10.1534/g3.113.007302
  • Mercken, E. M., Crosby, S. D., Lamming, D. W., JeBailey, L., Krzysik-Walker, S., Villareal, D. T., … Fontana, L. (2013). Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile. Aging Cell, 12(4), 645–51. http://doi.org/10.1111/acel.12088
  • Omodei, D., Licastro, D., Salvatore, F., Crosby, S. D., & Fontana, L. (2013). Serum from humans on long-term calorie restriction enhances stress resistance in cell culture. Aging, 5(8), 599–606. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/23912304
  • Hu, X., Yu, J., Crosby, S. D., & Storch, G. a. (2013). Gene expression profiles in febrile children with defined viral and bacterial infection. Proceedings of the National Academy of Sciences of the United States of America, 2013, 2–7. http://doi.org/10.1073/pnas.1302968110